The chemical industry in India is amongst the most dynamic and the largest sectors playing a fundamental role in the economic development of the country. N-Methyl-4-piperidone is part of the manufacturing of such chemicals. It is a colourless, odourless pale yellow liquid. It is used as antihypertensive agents during the making of 3-hydrazinopyridazines and y-carboline derivative as a potential serotonergic agent. It is also an impurity of the Loratadine. This product is stable under normal pressures and temperature and is highly admired for its salient features such as accuracy, precise proportions, long shelf life and being non-toxic.  The facilities for utilizing or storing this material must be equipped with both a safety shower facility and eyewash.

The other synonyms with which N-Carbethoxy-4-piperidone is associated includes;

•    ETHYL ESTER
•    1-PIPERIDINECARBOXYLIC ACID, 4-OXO
•    1-CARBETHOXY-4-PIPERIDONE
•    4-OXO-PIPERIDINE-1-CARBOXYLIC ACID ETHYL ESTER
•    4-PIPERIDONE-N-CARBOXYLIC ACID ETHYL ESTER
•    4-PIPERIDONE-1-CARBOXYLIC ACID ETHYL ESTER
•    ETHYL 4-OXOPIPERIDINE-1-CARBOXYLATE
•    ETHYL 4-PIPERIDONE-N-CARBOXYLATE
•    ETHYL 4-PIPERIDONE-1-CARBOXYLATE
•    AURORA KA-3057
•    N-ETHOXYCARBONYL-4-PIPERIDONE
•    4-Oxo-1-piperidinecarboxylic acid ethyl ester
•    N-Carboethoxy-4-piperidone
•    N-Carbithoxy-4-Piperidone
•    1-Ethoxycarbonyl-4-piperidone
•    Ethyl 4-Oxo-1-piperidinecarboxylate

Chemical Properties

•    Molecular Formula: C8H13NO3
•    Molecular Weight: 171.1937
•    Density: 1.135g per ml
•    Boiling Point: 95-98 degree Celsius (1mm Hg)
•    Solubility in water: it is slightly soluble
•    Storage information: N-Carbethoxy-4-piperidone is likely to darken during storage
•    Decomposition: carbon dioxide, toxic and irritating gases and fumes, nitrogen oxides and carbon monoxide

It is advisable not to pressurize, weld, cut, solder, 5-Nitro salicylic acid, braze, drill, grind or even expose the empty container to open flames, sparks or heat. In case of some forms of leakages or spills, absorb the spill with an inert material such as earth or dry sand and place it into an appropriate chemical waste container. Prevent runoff into ditchers and storm sewers which leads to waterways. Right away clean up the spills using appropriate protective equipment. Do away with every source of ignition and use spark-proof tools. Provide ventilation.

Handling and Storage of N-Carbethoxy-4-piperidone

Handling

•    Wash hands thoroughly after handling this product.
•    Avoid breathing gas, mist, vapour or dust
•    Use within an adequate ventilation
•    Avoid contact with clothing, eyes and skin
•    Avoid contact with sparks, flame and heat
•    An empty container retaining the product residue in the form of vapour or liquid or both can be dangerous. Hence it is advisable to keep the container tightly closed

Storage

•    Keep this product away from any source of ignition
•    Store it in an airtight container
•    Keep it in a well-ventilated, cool and dry area preferably away from any incompatible substances